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Neuropathic arthropathy (or neuropathic osteoarthropathy), also known as Charcot joint (often "Charcot foot"), refers to progressive degeneration of a weight bearing joint, a process marked by bony destruction, bone resorption, and eventual deformity. Onset is usually insidious. If this pathological process continues unchecked, it can result in joint deformity, ulceration and/or superinfection, loss of function, and in the worst-case scenario, amputation or death. Early identification of joint changes is the best way to limit morbidity. ==Pathogenesis== Any condition resulting in decreased peripheral sensation, proprioception, and fine motor control: *Diabetes mellitus neuropathy (the most common in the U.S. today, resulting in destruction of foot and ankle joints), with Charcot joints in 1/600-700 diabetics. Related to long-term poor glucose control. *Alcoholic neuropathy *Cerebral palsy *Leprosy *Syphilis (''tabes dorsalis''), caused by the organism ''Treponema pallidum'' *Spinal cord injury *Myelomeningocele *Syringomyelia *Intra-articular steroid injections *Congenital insensitivity to pain *Peroneal muscular atrophy 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Neuropathic arthropathy」の詳細全文を読む スポンサード リンク
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